Product Browser

Last updated: 2016/11/27
  • Related Product Showcase
  • By Research Area

  • By Disease

  • By Biomarker

Product Compare

Product Compare Cancel Click this icon to add products to compare list. Select up to 10 products.

Quick Order (Tutorial)

Input Catalog #,
place order here!
Catalog # :
  • Where to buy
  • Choose your location

HIRA monoclonal antibody, clone WC119.2H11

  • Catalog # : MAB8967
  • Visit Frequency :
  • Countries :
  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against partial recombinant HIRA.
  • Amount:
  • 100 uL
  • Immunogen:
  • Recombinant protein corresponding to amino acids 421-729 of human HIRA.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Specificity:
  • This antibody reacts with human HIRA.
  • Form:
  • Liquid
  • Purification:
  • Purified ascites
  • Concentration:
  • 1 ug/uL
  • Isotype:
  • IgG1
  • Recommend Usage:
  • The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.4 (0.02% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • Western blot analysis in Lane 1: 293 cells transfected with HIRA and Lane 2: 293 cells transfected withoud HIRA with HIRA monoclonal antibody, clone WC119.2H11 (Cat # MAB8967).
  • Application Image
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 7290
  • Gene Name:
  • HIRA
  • Gene Alias:
  • DGCR1,TUP1,TUPLE1
  • Gene Description:
  • HIR histone cell cycle regulation defective homolog A (S. cerevisiae)
  • Gene Summary:
  • This gene encodes a histone chaperone that preferentially places the variant histone H3.3 in nucleosomes. Orthologs of this gene in yeast, flies, and plants are necessary for the formation of transcriptionally silent heterochomatin. This gene plays an important role in the formation of the senescence-associated heterochromatin foci. These foci likely mediate the irreversible cell cycle changes that occur in senescent cells. It is considered the primary candidate gene in some haploinsufficiency syndromes such as DiGeorge syndrome, and insufficient production of the gene may disrupt normal embryonic development. [provided by RefSeq
  • Other Designations:
  • DiGeorge critical region gene 1,HIR histone cell cycle regulation defective homolog A
  • RSS
  • YouTube
  • Linkedin
  • Facebook