MCL1 monoclonal antibody, clone MCL.C9
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More Files
- More Functions
Western Blot (Tissue lysate)
Western blot analysis of MCL1 monoclonal antibody, clone MCL.C9 (Cat # MAB8825) in mouse B-cell lymphoma mouse transgenic model (lymph nodes from different mouse).
The upper bands represent 3 separate diseased lympho nodes and the spleen from the same transgenic mouse (Lane 1-4), along with lymphoid tissue from a nontransgenic littermate (Lane 5).
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Specification
Product Description
Mouse monoclonal antibody raised against recombinant MCL1.
Immunogen
Recombinant protein corresponding to human MCL1.
Host
Mouse
Reactivity
Human
Form
Liquid
Purification
Protein A purification
Concentration
1 ug/uL
Recommend Usage
The optimal working dilution should be determined by the end user.
Storage Buffer
In PBS, pH 7.4 (0.05% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of MCL1 monoclonal antibody, clone MCL.C9 (Cat # MAB8825) in mouse B-cell lymphoma mouse transgenic model (lymph nodes from different mouse).
The upper bands represent 3 separate diseased lympho nodes and the spleen from the same transgenic mouse (Lane 1-4), along with lymphoid tissue from a nontransgenic littermate (Lane 5).Enzyme-linked Immunoabsorbent Assay
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Gene Info — MCL1
Entrez GeneID
4170Gene Name
MCL1
Gene Alias
BCL2L3, EAT, MCL1L, MCL1S, MGC104264, MGC1839, TM
Gene Description
myeloid cell leukemia sequence 1 (BCL2-related)
Omim ID
159552Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene belongs to the Bcl-2 family. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified. The longer gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene product (isoform 2) promotes apoptosis and is death-inducing. [provided by RefSeq
Other Designations
OTTHUMP00000032794|OTTHUMP00000032795|induced myeloid leukemia cell differentiation protein Mcl-1|myeloid cell leukemia sequence 1|myeloid cell leukemia sequence 1, isoform 1
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Interactome
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Disease
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