IL17A monoclonal antibody
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant IL17A.
Immunogen
Recombinant protein corresponding to amino acids 25-155 of human IL17A.
Host
Mouse
Reactivity
Human
Specificity
This antibody recognizes recombinant IL17A.
Form
Liquid
Purification
Affinity purification
Concentration
1 ug/uL
Isotype
IgG2b
Recommend Usage
The optimal working dilution should be determined by the end user.
Storage Buffer
In citrate-Tris-HCl, pH 7.0 (0.02% Proclin 300).
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Enzyme-linked Immunoabsorbent Assay
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Gene Info — IL17A
Entrez GeneID
3605Protein Accession#
NM_002190Gene Name
IL17A
Gene Alias
CTLA8, IL-17, IL-17A, IL17
Gene Description
interleukin 17A
Omim ID
603149Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis. [provided by RefSeq
Other Designations
OTTHUMP00000016597|cytotoxic T-lymphocyte-associated antigen 8|cytotoxic T-lymphocyte-associated protein 8|cytotoxic T-lymphocyte-associated serine esterase 8|interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8)
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Interactome
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Pathway
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Disease
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