PROM1 monoclonal antibody, clone 487f5
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against recombinant PROM1.
Immunogen
Recombinant protein corresponding to human PROM1.
Host
Mouse
Reactivity
Human
Form
Liquid
Purification
Affinity purification
Isotype
IgG2b, kappa
Recommend Usage
The optimal working dilution should be determined by the end user.
Storage Buffer
In PBS, pH 7.4 (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
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Gene Info — PROM1
Entrez GeneID
8842Protein Accession#
NM_006017.2Gene Name
PROM1
Gene Alias
AC133, CD133, MSTP061, PROML1, RP41
Gene Description
prominin 1
Omim ID
604365Gene Ontology
HyperlinkGene Summary
This gene encodes a pentaspan transmembrane glycoprotein. The protein localizes to membrane protrusions and is often expressed on adult stem cells, where it is thought to function in maintaining stem cell properties by suppressing differentiation. Mutations in this gene have been shown to result in retinitis pigmentosa and Stargardt disease. Expression of this gene is also associated with several types of cancer. This gene is expressed from at least five alternative promoters that are expressed in a tissue-dependent manner. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
hProminin|hematopoietic stem cell antigen|prominin-like 1
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Interactome
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Disease
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Publication Reference
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Stemness Markers Detection In The Periphery Of Glioblastomas And Glioblastoma Ability To Generate Glioma Stem Cells: Clinical Correlations.
Soheila RD, Alessandro R, Hambra DV, Danilo P, Sabino L, Paola P, Benedetta C, Tempesta D, Coletti G, Cipolloni G, Grazia CM, Renato G.
World Neurosurgery 2017 May; 105:895.
Application:Flow Cyt, Human, Human glioma stem cells (GSCs).
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Immunophenotypic Characterization of Human Glioblastoma Stem Cells: Correlation with Clinical Outcome.
Miconi G, Palumbo P, Dehcordi SR, La Torre C, Lombardi F, Evtoski Z, Cimini AM, Galzio R, Cifone MG, Cinque B.
Journal of Cellular Biochemistry 2015 May; 116(5):864.
Application:Flow Cyt, Human, Glioblastoma multiforme cells.
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Stemness Markers Detection In The Periphery Of Glioblastomas And Glioblastoma Ability To Generate Glioma Stem Cells: Clinical Correlations.
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