EZR monoclonal antibody, clone 45j8
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant EZR.
Immunogen
Recombinant protein corresponding to amino acids 362-585 at C-terminus of human EZR.
Host
Mouse
Reactivity
Bovine, Hamster, Human, Kangaroo, Monkey, Mouse
Form
Liquid
Purification
In ascites
Concentration
1 ug/uL
Isotype
IgG
Recommend Usage
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4 (0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of chicken fibroblast cell extract with EZR monoclonal antibody, clone 45j8 (Cat # MAB8812) at 1 : 2000 dilution.Immunohistochemistry
Immunocytochemistry
Immunoprecipitation
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Gene Info — EZR
Entrez GeneID
7430Gene Name
EZR
Gene Alias
CVIL, CVL, DKFZp762H157, FLJ26216, MGC1584, VIL2
Gene Description
ezrin
Omim ID
123900Gene Ontology
HyperlinkGene Summary
The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000017506|OTTHUMP00000017507|cytovillin 2|villin 2 (ezrin)
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Interactome
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