TCEB2 monoclonal antibody, clone 9y74
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Specification
Product Description
Mouse monoclonal antibody raised against full length recombinant TCEB2.
Immunogen
Recombinant protein corresponding to full length human TCEB2.
Host
Mouse
Reactivity
Human
Specificity
This antibody recognizes recombinant protein TCEB2.
Form
Liquid
Purification
Affinity purification
Concentration
1 ug/uL
Isotype
IgG1
Recommend Usage
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In citrate-Tris-HCl, pH 7.0 (0.02% Proclin 300)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Western Blot (Recombinant protein)
Western blot analysis in TCEB2 recombinant protein with TCEB2 monoclonal antibody, clone 9y74 (Cat # MAB8790) at 1 : 1000 dilution.Enzyme-linked Immunoabsorbent Assay
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Gene Info — TCEB2
Entrez GeneID
6923Protein Accession#
NM_007108Gene Name
TCEB2
Gene Alias
ELOB, SIII
Gene Description
transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B)
Omim ID
600787Gene Ontology
HyperlinkGene Summary
This gene encodes the protein elongin B, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene. Pseudogenes have been identified on chromosomes 11 and 13. [provided by RefSeq
Other Designations
RNA polymerase II transcription factor SIII p18 subunit|SIII p18|elongin B|elongin, 18-kD subunit|transcription elongation factor B (SIII), polypeptide 2 (18kD, elongin B)
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Interactome
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Pathway
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