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Last updated: 2017/3/26
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ABCA1 monoclonal antibody, clone AB.H10

  • Catalog # : MAB8772
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against synthetic peptide of ABCA1.
  • Immunogen:
  • A synthetic peptide corresponding to amino acids 1800-2260 at C-terminus end of human ABCA1.
  • Host:
  • Mouse
  • Reactivity:
  • Chicken, Human, Mouse
  • Form:
  • Liquid
  • Purification:
  • Protein A purification
  • Concentration:
  • 1 ug/uL
  • Recommend Usage:
  • Western Blot (1:1000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.4 (0.05% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis of ABCA1 induction by cholesterol (+) in human fibroblast cells from different patients (1, 2, 3, 4). Simultaneous bloting with anti-actin antibody was used for protein loading control.
  • Immunohistochemistry
  • Immunoprecipitation
  • ELISA
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Immunohistochemistry
  • Immunoprecipitation
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 19
  • Gene Name:
  • ABCA1
  • Gene Alias:
  • ABC-1,ABC1,CERP,FLJ14958,HDLDT1,MGC164864,MGC165011,TGD
  • Gene Description:
  • ATP-binding cassette, sub-family A (ABC1), member 1
  • Gene Summary:
  • The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. With cholesterol as its substrate, this protein functions as a cholesteral efflux pump in the cellular lipid removal pathway. Mutations in this gene have been associated with Tangier's disease and familial high-density lipoprotein deficiency. [provided by RefSeq
  • Other Designations:
  • ATP binding cassette transporter 1,ATP-binding cassette 1,ATP-binding cassette, sub-family A member 1,OTTHUMP00000021833,cholesterol efflux regulatory protein,membrane-bound
  • Gene Pathway
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