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Last updated: 2016/11/27
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GNRHR monoclonal antibody, clone AT2.G7

  • Catalog # : MAB8771
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against synthetic peptide of GNRHR.
  • Immunogen:
  • A mixture of peptides from different regions of human GNRHR.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Protein A purification
  • Concentration:
  • 1 ug/uL
  • Recommend Usage:
  • Western Blot (1:1000)
    Immunohistochemistry (1:200)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.4 (0.05% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • Western blot analysis of GNRHR monoclonal antibody, clone AT2.G7 (Cat # MAB8771) in GNRHR protein.
    Lane 1 and 2 : Tissue extracts from normal ovaries.
    Lane 3 to 9 : Tissue extracts from different stage of ovarian cancers.
  • Immunohistochemistry
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • Immunohistochemistry
  • Gene Information
  • Entrez GeneID:
  • 2798
  • Gene Name:
  • GNRHR
  • Gene Alias:
  • GNRHR1,GRHR,LHRHR,LRHR
  • Gene Description:
  • gonadotropin-releasing hormone receptor
  • Gene Summary:
  • This gene encodes the receptor for type 1 gonadotropin-releasing hormone. This receptor is a member of the seven-transmembrane, G-protein coupled receptor (GPCR) family. It is expressed on the surface of pituitary gonadotrope cells as well as lymphocytes, breast, ovary, and prostate. Following binding of gonadotropin-releasing hormone, the receptor associates with G-proteins that activate a phosphatidylinositol-calcium second messenger system. Activation of the receptor ultimately causes the release of gonadotropic luteinizing hormone (LH) and follicle stimulating hormone (FSH). Defects in this gene are a cause of hypogonadotropic hypogonadism (HH). Alternative splicing results in multiple transcript variants encoding different isoforms. More than 18 transcription initiation sites in the 5' region and multiple polyA signals in the 3' region have been identified for this gene. [provided by RefSeq
  • Other Designations:
  • gonadotropin-releasing hormone (type 1) receptor 1,leutinizing hormone releasing horomone receptor,leutinizing-releasing hormone receptor,luliberin receptor,type I GnRH receptor
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