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Last updated: 2017/6/18
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PKM2 monoclonal antibody

  • Catalog # : MAB8733
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against partial recombinant PKM2.
  • Immunogen:
  • Recombinant protein corresponding to N-terminus residues of human PKM2.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Specificity:
  • This antibody is specific to PKM2.
  • Form:
  • Liquid
  • Purification:
  • Protein G purification
  • Concentration:
  • 1 mg/mL
  • Recommend Usage:
  • Western Blot (1:100-1:2000)
    ELISA (1:5000-1:20000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.4 (0.02% sodium azide, 1% BSA, 50% glycerol)
  • Storage Instruction:
  • Store at 4°C for three months. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Recombinant protein)
  • Western Blot (Recombinant protein)
  • Western blot analysis of PKM2 monoclonal antibody (Cat # MAB8733) at 1 : 2000 dilution interacts with recombinant PKM2 protein with a DsbA tag. Predicted band size : 45 KDa. Observed band size : 45 KDa.
  • ELISA
  • Application Image
  • Western Blot (Recombinant protein)
  • Western Blot (Recombinant protein)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 5315
  • Gene Name:
  • PKM2
  • Gene Alias:
  • CTHBP,MGC3932,OIP3,PK3,PKM,TCB,THBP1
  • Gene Description:
  • pyruvate kinase, muscle
  • Gene Summary:
  • This gene encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and pyruvate. This protein has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis. Three alternatively spliced transcript variants encoding two distinct isoforms have been reported. [provided by RefSeq
  • Other Designations:
  • OPA-interacting protein 3,PK, muscle type,pyruvate kinase M2,thyroid hormone-binding protein, cytosolic
  • Interactome
  • Interactome
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