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Last updated: 2016/12/4
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TLR4 monoclonal antibody

  • Catalog # : MAB8720
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against synthetic peptide of TLR4.
  • Immunogen:
  • A synthetic peptide (conjugated with KLH) corresponding to N-terminus residues of human TLR4.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Specificity:
  • This antibody is specific to TLR4.
  • Form:
  • Liquid
  • Purification:
  • Protein G purification
  • Concentration:
  • 1 mg/mL
  • Recommend Usage:
  • Western Blot (1:100-1:2000)
    ELISA (1:5000-1:20000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.4 (0.02% sodium azide, 1% BSA, 50% glycerol)
  • Storage Instruction:
  • Store at 4°C for three months. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis of TLR4 monoclonal antibody (Cat # MAB8720) at 1 : 1000 dilution. HeLa whole cell lysate 40 ug. Predicted band size : 90 KDa. Observed band size : 100 KDa.
  • ELISA
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 7099
  • Gene Name:
  • TLR4
  • Gene Alias:
  • ARMD10,CD284,TOLL,hToll
  • Gene Description:
  • toll-like receptor 4
  • Gene Summary:
  • The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor is most abundantly expressed in placenta, and in myelomonocytic subpopulation of the leukocytes. It has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. Mutations in this gene have been associated with differences in LPS responsiveness. Also, several transcript variants of this gene have been found, but the protein coding potential of most of them is uncertain. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000022807,homolog of Drosophila toll
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