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Last updated: 2017/11/19
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PPP1CA monoclonal antibody

  • Catalog # : MAB8715
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against full length recombinant PPP1CA.
  • Immunogen:
  • Recombinant protein corresponding to full length human PPP1CA.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Specificity:
  • This antibody is specific to PPP1CA.
  • Form:
  • Liquid
  • Purification:
  • Protein G purification
  • Concentration:
  • 1 mg/mL
  • Recommend Usage:
  • Western Blot (1:100-1:2000)
    ELISA (1:5000-1:20000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.4 (0.02% sodium azide, 1% BSA, 50% glycerol)
  • Storage Instruction:
  • Store at 4°C for three months. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis of PPP1CA monoclonal antibody (Cat # MAB8715) at 1 : 1000 dilution. Lane1 : MCF-7 whole cell lysate 30 ug/lane. Lane 2 : K-562 whole cell lysate 30 ug/lane. Lane 3 : HeLa whole cell lysate 30 ug/lane. Lane 4 : HepG2 whole cell lysate 30 ug/lane. Lane 5 : Jurkat whole cell lysate 30 ug/lane. Predicted band size : 38 KDa. Observed band size : 38 KDa.
  • ELISA
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 5499
  • Gene Name:
  • PPP1CA
  • Gene Alias:
  • MGC15877,MGC1674,PP-1A,PPP1A
  • Gene Description:
  • protein phosphatase 1, catalytic subunit, alpha isoform
  • Gene Summary:
  • The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Increased PP1 activity has been observed in the end stage of heart failure. Studies in both human and mice suggest that PP1 is an important regulator of cardiac function. Mouse studies also suggest that PP1 functions as a suppressor of learning and memory. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • protein phosphatase 1, catalytic subunit, alpha,serine/threonine protein phosphatase PP1-alpha 1 catalytic subunit
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