LY9 monoclonal antibody, clone HLy9.25
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Specification
Product Description
Mouse monoclonal antibody raised against full length recombinant LY9.
Immunogen
Recombinant protein corresponding to full length human LY9.
Host
Mouse
Reactivity
Human
Specificity
This antibody is specific to LY9.
Form
Liquid
Purification
Protein A purification
Isotype
IgG1
Recommend Usage
The optimal working dilution should be determined by the end user.
Storage Buffer
In PBS, pH 7.4 (0.09% sodium azide)
Storage Instruction
Store at 4°C. Do not freeze.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Immunocytochemistry
Functional Study
Flow Cytometry
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Gene Info — LY9
Entrez GeneID
4063Gene Name
LY9
Gene Alias
CD229, SLAMF3, hly9, mLY9
Gene Description
lymphocyte antigen 9
Omim ID
600684Gene Ontology
HyperlinkGene Summary
LY9 belongs to the SLAM family of immunomodulatory receptors (see SLAMF1; MIM 603492) and interacts with the adaptor molecule SAP (SH2D1A; MIM 300490) (Graham et al., 2006 [PubMed 16365421]).[supplied by OMIM
Other Designations
OTTHUMP00000025675|T-lymphocyte surface antigen Ly-9|cell-surface molecule Ly-9
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Interactome
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Disease
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Publication Reference
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Human Ly9 (CD229) as novel tumor-associated antigen (TAA) in chronic lymphocytic leukemia (B-CLL) recognized by autologous CD8+ T cells.
Bund D, Mayr C, Kofler DM, Hallek M, Wendtner CM.
Experimental Hematology 2006 Jul; 34(7):860.
Application:Flow Cyt, Human, B-CLL cells.
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Identification of Grb2 as a novel binding partner of the signaling lymphocytic activation molecule-associated protein binding receptor CD229.
Martin M, Del Valle JM, Saborit I, Engel P.
Journal of Immunology 2005 May; 174(10):5977.
Application:Func, Human, Monkey, COS-7 cells, Jurkat cells, PBMCs.
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Differential expression of SAP and EAT-2-binding leukocyte cell-surface molecules CD84, CD150 (SLAM), CD229 (Ly9) and CD244 (2B4).
Romero X, Benitez D, March S, Vilella R, Miralpeix M, Engel P.
Tissue Antigens 2004 Aug; 64(2):132.
Application:Flow Cyt, Human, NK cells, T cells, Thymocytes from peripheral blood.
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Human Ly9 (CD229) as novel tumor-associated antigen (TAA) in chronic lymphocytic leukemia (B-CLL) recognized by autologous CD8+ T cells.
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