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Last updated: 2017/3/19
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CEACAM1/CEACAM6/CEACAM3/CEACAM5 monoclonal antibody, clone CLB-gran/10

  • Catalog # : MAB8702
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against full length native CEACAM1/CEACAM6/CEACAM3/CEACAM5.
  • Immunogen:
  • Native purified CEACAM1/CEACAM6/CEACAM3/CEACAM5 from human granulocytes.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Specificity:
  • This antibody is specific to CEACAM1/6/3/5.
  • Form:
  • Liquid
  • Purification:
  • Protein A purification
  • Concentration:
  • 1 mg/mL
  • Isotype:
  • IgG1
  • Recommend Usage:
  • The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In TBS, pH 8.0 (0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C. Do not freeze.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot
  • Immunocytochemistry
  • Flow Cytometry
  • Application Image
  • Western Blot
  • Immunocytochemistry
  • Flow Cytometry
  • Gene Information
  • Entrez GeneID:
  • 634
  • Gene Name:
  • CEACAM1
  • Gene Alias:
  • BGP,BGP1,BGPI
  • Gene Description:
  • carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
  • Gene Summary:
  • This gene encodes a member of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily. Two subgroups of the CEA family, the CEA cell adhesion molecules and the pregnancy-specific glycoproteins, are located within a 1.2 Mb cluster on the long arm of chromosome 19. Eleven pseudogenes of the CEA cell adhesion molecule subgroup are also found in the cluster. The encoded protein was originally described in bile ducts of liver as biliary glycoprotein. Subsequently, it was found to be a cell-cell adhesion molecule detected on leukocytes, epithelia, and endothelia. The encoded protein mediates cell adhesion via homophilic as well as heterophilic binding to other proteins of the subgroup. Multiple cellular activities have been attributed to the encoded protein, including roles in the differentiation and arrangement of tissue three-dimensional structure, angiogenesis, apoptosis, tumor suppression, metastasis, and the modulation of innate and adaptive immune responses. Multiple transcript variants encoding different isoforms have been reported, but the full-length nature of only two has been determined. [provided by RefSeq
  • Other Designations:
  • CD66a antigen,antigen CD66,biliary glycoprotein adhesion molecule,carcinoembryonic antigen-related cell adhesion molecule 1
  • Gene Information
  • Entrez GeneID:
  • 4680
  • Gene Name:
  • CEACAM6
  • Gene Alias:
  • CD66c,CEAL,NCA
  • Gene Description:
  • carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
  • Gene Summary:
  • Carcinoembryonic antigen (CEA; MIM 114890) is one of the most widely used tumor markers in serum immunoassay determinations of carcinoma. An apparent lack of absolute cancer specificity for CEA probably results in part from the presence in normal and neoplastic tissues of antigens that share antigenic determinants with the 180-kD form of CEA (Barnett et al., 1988 [PubMed 3220478]). For background information on the CEA family of genes, see CEACAM1 (MIM 109770).[supplied by OMIM
  • Other Designations:
  • -
  • Gene Information
  • Entrez GeneID:
  • 1084
  • Gene Name:
  • CEACAM3
  • Gene Alias:
  • CD66D,CEA,CGM1,MGC119875,W264,W282
  • Gene Description:
  • carcinoembryonic antigen-related cell adhesion molecule 3
  • Gene Summary:
  • This gene encodes a member of the family of carcinoembryonic antigen-related cell adhesion molecules (CEACAMs), which are used by several bacterial pathogens to bind and invade host cells. The encoded transmembrane protein directs phagocytosis of several bacterial species that is dependent on the small GTPase Rac. It is thought to serve an important role in controlling human-specific pathogens by the innate immune system. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq
  • Other Designations:
  • CD66d antigen,carcinoembryonic antigen CGM1,carcinoembryonic antigen gene family member 1,nonspecific cross-reacting antigen
  • Gene Information
  • Entrez GeneID:
  • 1048
  • Gene Name:
  • CEACAM5
  • Gene Alias:
  • CD66e,CEA,DKFZp781M2392
  • Gene Description:
  • carcinoembryonic antigen-related cell adhesion molecule 5
  • Other Designations:
  • -
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