Western blot analysis of Lane 1: Jurkat cell lysate, Lane 2: 293T cell lysate, Lane 3: A431 cell lysate, Lane 4: HeLa cell lysate.
Immunocytochemistry
Immunofluorescence
Immunofluorescence of human HeLa cells stained with Hoechst 3342 (Blue) for nucleus staining and LDHA monoclonal antibody, clone AT1A4 (Cat # MAB8700) (1 : 500) with Texas Red (Red).
The protein encoded by this gene catalyzes the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis. The protein is found predominantly in muscle tissue and belongs to the lactate dehydrogenase family. Mutations in this gene have been linked to exertional myoglobinuria. Multiple transcript variants encoding different isoforms have been found for this gene. The human genome contains several non-transcribed pseudogenes of this gene. [provided by RefSeq