GYPA monoclonal antibody, clone CMRF14
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Specification
Product Description
Mouse monoclonal antibody raised against full length native GYPA.
Immunogen
Native purified GYPA from human Red blood cells.
Host
Mouse
Reactivity
Human
Specificity
This antibody is specific to GYPA.
Form
Liquid
Isotype
IgG2b
Recommend Usage
Flow cytometry (1 ug/106 cells)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS
Storage Instruction
Store at 4°C.
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Applications
Flow Cytometry
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Gene Info — GYPA
Entrez GeneID
2993Gene Name
GYPA
Gene Alias
CD235a, GPA, GPErik, GPSAT, GpMiIII, HGpMiIII, HGpMiV, HGpMiX, HGpMiXI, HGpSta(C), MN, MNS
Gene Description
glycophorin A (MNS blood group)
Gene Ontology
HyperlinkGene Summary
Glycophorins A (GYPA) and B (GYPB) are major sialoglycoproteins of the human erythrocyte membrane which bear the antigenic determinants for the MN and Ss blood groups. In addition to the M or N and S or s antigens that commonly occur in all populations, about 40 related variant phenotypes have been identified. These variants include all the variants of the Miltenberger complex and several isoforms of Sta, as well as Dantu, Sat, He, Mg, and deletion variants Ena, S-s-U- and Mk. Most of the variants are the result of gene recombinations between GYPA and GYPB. [provided by RefSeq
Other Designations
Mi.V glycoprotein (24 AA)|erythroid-lineage-specific membrane sialoglycoprotein|glycophorin A|glycophorin A (MN blood group)|glycophorin A MNS blood group|glycophorin A, GPA|glycophorin Erik|glycophorin MiI|glycophorin MiIII|glycophorin MiV|glycophorin Mi
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Interactome
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Pathway
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Disease
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Publication Reference
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Red blood cell glycophorins.
Chasis JA, Mohandas N.
Blood 1992 Oct; 80(8):1869.
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Flow cytometric characterization of normal and variant cells with monoclonal antibodies specific for glycophorin A.
Langlois RG, Bigbee WL, Jensen RH.
Journal of Immunology 1985 Jun; 134(6):4009.
Application：Flow Cyt, Chimpanzee, Human, Chimpanzee erythrocytes, K-562 cells.
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Red blood cell glycophorins.
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