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Last updated: 2016/10/23
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HIST2H3A monoclonal antibody, clone 6D10H9

  • Catalog # : MAB8548
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against synthetic peptide of HIST2H3A.
  • Immunogen:
  • A synthetic peptide corresponding to human HIST2H3A.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Specificity:
  • This antibody is not only able to bind to H3R2a, but also distinguish two forms (Asymmetric and Symmetric) of H3R2. It specifically detected protein derived from cell lysates in both ELISA and WB.
  • Form:
  • Lyophilized
  • Isotype:
  • IgG1
  • Recommend Usage:
  • ELISA (1:5000-1:8000)
    Western Blot (1-2 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • Lyophilized from PBS, pH 7.5, 0.1% BSA.
  • Storage Instruction:
  • Store at -20°C.
    Aliquot after reconstitution to avoid repeated freezing and thawing.
  • Applications
  • Western Blot
  • Application Image
  • Western Blot
  • Gene Information
  • Gene Name:
  • HIST2H3A
  • Gene Alias:
  • H3/n,H3/o
  • Gene Description:
  • histone cluster 2, H3a
  • Gene Summary:
  • Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated; this record represents the centromeric copy. [provided by RefSeq
  • Other Designations:
  • histone 2, H3a,histone H3/o
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