TRA monoclonal antibody, clone IP26
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Specification
Product Description
Mouse monoclonal antibody raised against TRA.
Immunogen
Human TRA.
Host
Mouse
Reactivity
Human
Specificity
The dominant subtype of T cell receptor expressed in human peripheral blood.
Form
Liquid
Isotype
IgG1
Recommend Usage
The optimal working dilution should be determined by the end user.
Storage Buffer
In PBS, pH 7.4 (0.09% sodium azide)
Storage Instruction
Store at 4°C. Do not freeze.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Flow Cytometry
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Gene Info — TRA
Entrez GeneID
6955Gene Name
TRA
Gene Alias
FLJ22602, MGC117436, MGC22624, MGC23964, MGC71411, TCRA, TCRD, TRA
Gene Description
T cell receptor alpha locus
Omim ID
186880Gene Ontology
HyperlinkGene Summary
alpha polypeptide|T-cell receptor
Other Designations
T-cell antigen receptor, alpha polypeptide|T-cell receptor, alpha (V,D,J,C)
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Interactome
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Disease
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Publication Reference
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Downregulation of the T-cell receptor complex and impairment of T-cell activation by human herpesvirus 6 u24 protein.
Sullivan BM, Coscoy L.
Journal of Virology 2008 Jan; 82(2):602.
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Recombinant anti-CD4 antibody 13B8.2 blocks membrane-proximal events by excluding the Zap70 molecule and downstream targets SLP-76, PLC gamma 1, and Vav-1 from the CD4-segregated Brij 98 detergent-resistant raft domains.
Chentouf M, Ghannam S, Bes C, Troadec S, Cerutti M, Chardes T.
Journal of Immunology 2007 Jul; 179(1):409.
Application:WB-Ce, Human, Jurkat T cells.
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Significance of circulating T-cell clones in Sezary syndrome.
Ortonne N, Huet D, Gaudez C, Marie-Cardine A, Schiavon V, Bagot M, Musette P, Bensussan A.
Blood 2006 May; 107(10):4030.
Application:Flow Cyt, Human, Human T cells.
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SC5 mAb represents a unique tool for the detection of extracellular vimentin as a specific marker of Sezary cells.
Huet D, Bagot M, Loyaux D, Capdevielle J, Conraux L, Ferrara P, Bensussan A, Marie-Cardine A.
Journal of Immunology 2006 Jan; 176(1):652.
Application:Flow Cyt, IF, IP, WB, Human, COS, HUT 78 cells, PBMCs.
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Downregulation of the T-cell receptor complex and impairment of T-cell activation by human herpesvirus 6 u24 protein.
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