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Last updated: 2016/12/4
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CASP7 monoclonal antibody, clone B4-G2

  • Catalog # : MAB8485
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against synthetic peptide of CASP7.
  • Immunogen:
  • A synthetic peptide corresponding to human CASP7.
  • Host:
  • Mouse
  • Reactivity:
  • Human, Mouse, Rat
  • Specificity:
  • Detects both pro-caspase-7 (34 KDa) and the large subunit of cleaved caspase-7 (19 KDa) in apoptosis cells on SDS-PAGE immunoblots.
  • Form:
  • Liquid
  • Isotype:
  • IgG1
  • Recommend Usage:
  • Western Blot (0.5-2 ug/mL)
    Immunoprecipitation (4-10 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (50% glycerol, 1 mg/ml BSA, 1.5 mM thimerosal)
  • Storage Instruction:
  • Store at -20°C. For long term storage store at -80°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains thimerosal: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot
  • Immunoprecipitation
  • Application Image
  • Western Blot
  • Immunoprecipitation
  • Gene Information
  • Entrez GeneID:
  • 840
  • Gene Name:
  • CASP7
  • Gene Alias:
  • CMH-1,ICE-LAP3,MCH3
  • Gene Description:
  • caspase 7, apoptosis-related cysteine peptidase
  • Gene Summary:
  • This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of this caspase is cleaved by caspase 3 and 10. It is activated upon cell death stimuli and induces apoptosis. Alternative splicing results in four transcript variants, encoding three distinct isoforms. [provided by RefSeq
  • Other Designations:
  • ICE-like apoptotic protease 3,Lice2 alpha/beta/gamma,OTTHUMP00000020510,OTTHUMP00000020511,OTTHUMP00000020512,OTTHUMP00000020514,apoptotic protease MCH-3,caspase 7,caspase 7 isoform delta,caspase 7, apoptosis-related cysteine protease
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