GPC1 monoclonal antibody, clone 9E9
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Specification
Product Description
Mouse monoclonal antibody raised against full length recombinant GPC1.
Immunogen
Recombinant protein corresponding to full length human GPC1.
Host
Mouse
Reactivity
Human, Mouse
Specificity
This antibody recognizes native and recombinant human and mouse glypican-1.
Form
Liquid
Isotype
IgG1
Recommend Usage
ELISA (1-5 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Western Blot (Tissue lysate)
Western blot analysis in normal mouse brain with GPC1 monoclonal antibody, clone 9E9 (Cat # MAB8351). A band of approx. 64 kDa is detected.Immunofluorescence
Immunofluorescence staining of human pancreatic carcinoma cell line Capan-1 with Western blot analysis in normal mouse brain with GPC1 monoclonal antibody, clone 9E9 (Cat # MAB8351).Enzyme-linked Immunoabsorbent Assay
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Gene Info — GPC1
Entrez GeneID
2817Gene Name
GPC1
Gene Alias
FLJ38078, glypican
Gene Description
glypican 1
Omim ID
600395Gene Ontology
HyperlinkGene Summary
Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. [provided by RefSeq
Other Designations
glypican proteoglycan 1
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Interactome
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Disease
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Publication Reference
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Regulation of bone morphogenetic protein signalling and cranial osteogenesis by Gpc1 and Gpc3.
Dwivedi PP, Grose RH, Filmus J, Hii CS, Xian CJ, Anderson PJ, Powell BC.
Bone 2013 Aug; 55(2):367.
Application:WB, Human, Human suture mesenchymal cells.
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Regulation of bone morphogenetic protein signalling and cranial osteogenesis by Gpc1 and Gpc3.
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