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Last updated: 2016/12/4
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TPO monoclonal antibody, clone 6G12

  • Catalog # : MAB8343
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against TPO.
  • Immunogen:
  • Purified human TPO.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Specificity:
  • These antibodies react specifically with human thyroid peroxidase.
  • Form:
  • Liquid
  • Isotype:
  • IgG1
  • Recommend Usage:
  • The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.4 (0.09% sodium azide)
  • Storage Instruction:
  • Store at -20°C. For long term storage store at -80°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • ELISA
  • Application Image
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 7173
  • Gene Name:
  • TPO
  • Gene Alias:
  • MSA,TPX
  • Gene Description:
  • thyroid peroxidase
  • Gene Summary:
  • This gene encodes a membrane-bound glycoprotein. The encoded protein acts as an enzyme and plays a central role in thyroid gland function. The protein functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. Mutations in this gene are associated with several disorders of thyroid hormonogenesis, including congenital hypothyroidism, congenital goiter, and thyroid hormone organification defect IIA. Multiple transcript variants encoding distinct isoforms have been identified for this gene. Additional splice variants have been described but their biological natures have not been determined. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000115304,OTTHUMP00000115536,thyroid microsomal antigen,thyroperoxidase
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