ELK1 monoclonal antibody, clone 3H6D12, 4H9C8,4H9F1
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More Files
- More Functions
Western Blot
Western blot analysis using ELK1 monoclonal antibody, clone 3H6D12, 4H9C8,4H9F1 (Cat # MAB8302) against truncated recombinant ELK1 (Lane 1) and K-562 cell lysate (Lane 2).
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunoistochemical analysis of paraffin-embedded human brain tumor tissue showing nuclear/cytoplasmic localization using ELK1 with DAB staining.
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant ELK1.
Immunogen
Recombinant protein corresponding to truncated human ELK1.
Host
Mouse
Reactivity
Human
Form
Liquid
Isotype
IgG1
Recommend Usage
Western Blot (1:500-1:1000)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:500-1:1000)br>ELISA (1:10000)
The optimal working dilution should be determined by the end user.Storage Buffer
In ascites
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Western Blot
Western blot analysis using ELK1 monoclonal antibody, clone 3H6D12, 4H9C8,4H9F1 (Cat # MAB8302) against truncated recombinant ELK1 (Lane 1) and K-562 cell lysate (Lane 2).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunoistochemical analysis of paraffin-embedded human brain tumor tissue showing nuclear/cytoplasmic localization using ELK1 with DAB staining.Enzyme-linked Immunoabsorbent Assay
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Gene Info — ELK1
Entrez GeneID
2002Gene Name
ELK1
Gene Alias
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Gene Description
ELK1, member of ETS oncogene family
Omim ID
311040Gene Ontology
HyperlinkGene Summary
This gene is a member of the Ets family of transcription factors and of the ternary complex factor (TCF) subfamily. Proteins of the TCF subfamily form a ternary complex by binding to the the serum response factor and the serum reponse element in the promoter of the c-fos proto-oncogene. The protein encoded by this gene is a nuclear target for the ras-raf-MAPK signaling cascade. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq
Other Designations
ELK1 protein|OTTHUMP00000023224|OTTHUMP00000023225
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Interactome
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Pathway
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Disease
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Publication Reference
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PKCalpha expression regulated by Elk-1 and MZF-1 in human HCC cells.
Hsieh YH, Wu TT, Tsai JH, Huang CY, Hsieh YS, Liu JY.
Biochemical and Biophysical Research Communications 2006 Jan; 339(1):217.
Application：ChIP, Human, HA22T/VGH cells.
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Activation of ternary complex factor Elk-1 by stress-activated protein kinases.
Gille H, Strahl T, Shaw PE.
Current Biology 1995 Oct; 5(10):1191.
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ERK phosphorylation potentiates Elk-1-mediated ternary complex formation and transactivation.
Gille H, Kortenjann M, Thomae O, Moomaw C, Slaughter C, Cobb MH, Shaw PE.
The EMBO Journal 1995 Mar; 14(5):951.
Application：Func, WB-Re, Monkey, COS cells, Recombinant proteins.
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PKCalpha expression regulated by Elk-1 and MZF-1 in human HCC cells.
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