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Last updated: 2017/3/19
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DNM1 monoclonal antibody, clone 3G4B6

  • Catalog # : MAB8301
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against partial recombinant DNM1.
  • Immunogen:
  • Recombinant protein corresponding to truncated human DNM1.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Isotype:
  • IgG2a
  • Recommend Usage:
  • Western Blot (1:500-1:2000)
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:500-1:2000)
    Immunohistochemistry (Frozen sections) (1:500-1:2000)
    ELISA (1:10000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In ascites
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Publication Reference
  • Applications
  • Western Blot
  • Western Blot
  • Western blot analysis using DNM1 monoclonal antibody, clone 3G4B6 (Cat # MAB8301) against truncated DNM1 recombinant protein (Lane 1), SK-N-SH (Lane 2) and NIH/3T3 (Lane 3) cell lysate.
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical analysis of paraffin-embedded human lymph tissue (A), glioma tissue (B) and cerebellum tissue (C), showing membrane localization using DNM1 monoclonal antibody, clone 3G4B6 (Cat # MAB8301) with DAB staining.
  • Immunohistochemistry (Frozen sections)
  • ELISA
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Immunohistochemistry (Frozen sections)
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 1759
  • Gene Name:
  • DNM1
  • Gene Alias:
  • DNM
  • Gene Description:
  • dynamin 1
  • Gene Summary:
  • This gene encodes a member of the dynamin subfamily of GTP-binding proteins. The encoded protein possesses unique mechanochemical properties used to tubulate and sever membranes, and is involved in clathrin-mediated endocytosis and other vesicular trafficking processes. Actin and other cytoskeletal proteins act as binding partners for the encoded protein, which can also self-assemble leading to stimulation of GTPase activity. More than sixty highly conserved copies of the 3' region of this gene are found elsewhere in the genome, particularly on chromosomes Y and 15. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq
  • Other Designations:
  • -
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