KRT1 monoclonal antibody, clone 3C10F7, 3C10G5
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant KRT1.
Immunogen
Recombinant protein corresponding to truncated human KRT1.
Host
Mouse
Reactivity
Human
Form
Liquid
Isotype
IgG1
Recommend Usage
Western Blot (1:500-1:2000)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:500-1:2000)
Immunohistochemistry (Frozen sections) (1:500-1:2000)
ELISA (1:10000)
The optimal working dilution should be determined by the end user.Storage Buffer
In ascites
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Western Blot (Recombinant protein)
Western blot analysis using KRT1 monoclonal antibody, clone 3C10F7, 3C10G5 (Cat # MAB8298) against truncated KRT1 recombinant protein.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of paraffin-embedded human liver tissue (A), colon carcinoma (B), lung carcinoma (C) and esophagus tissue (D), showing membrane localization using KRT1 monoclonal antibody, clone 3C10F7, 3C10G5 (Cat # MAB8298) with DAB staining.Immunohistochemistry (Frozen sections)
Enzyme-linked Immunoabsorbent Assay
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Gene Info — KRT1
Entrez GeneID
3848Gene Name
KRT1
Gene Alias
CK1, EHK1, K1, KRT1A
Gene Description
keratin 1
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the spinous and granular layers of the epidermis with family member KRT10 and mutations in these genes have been associated with bullous congenital ichthyosiform erythroderma. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. [provided by RefSeq
Other Designations
cytokeratin 1|epidermolytic hyperkeratosis 1|hair alpha protein|keratin, type II cytoskeletal 1
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