Mouse monoclonal antibody raised against partial recombinant KRT1.
Recombinant protein corresponding to truncated human KRT1.
Western Blot (1:500-1:2000) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:500-1:2000) Immunohistochemistry (Frozen sections) (1:500-1:2000) ELISA (1:10000) The optimal working dilution should be determined by the end user.
Store at -20°C. Aliquot to avoid repeated freezing and thawing.
The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the spinous and granular layers of the epidermis with family member KRT10 and mutations in these genes have been associated with bullous congenital ichthyosiform erythroderma. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. [provided by RefSeq
cytokeratin 1,epidermolytic hyperkeratosis 1,hair alpha protein,keratin, type II cytoskeletal 1