Mouse monoclonal antibody raised against partial recombinant TSG1.
Recombinant protein corresponding to amino acids 167-374 of TSG1.
This antibody recognizes TSG101 protein, the product of a recently identified tumor susceptibility gene. Inactivation of this gene in a mouse fibroblast system results in cell transformation and permits those cells to form tumors in nude mice. The TSG101 gene encodes a 46 kD protein containing a proline-rich domain and a leucine-zipper motif within a coiled-coil domain near the C-terminus.
Western Blot (0.5-2 ug/mL) Immunoprecipitation (0.5-2 ug/mL) The optimal working dilution should be determined by the end user.
Store at -80°C. Aliquot to avoid repeated freezing and thawing.