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Last updated: 2017/1/15
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NAMPT monoclonal antibody, clone AF-1E12

  • Catalog # : MAB8231
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against full length recombinant NAMPT.
  • Immunogen:
  • Recombinant His fusion protein corresponding to full length human NAMPT.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Specificity:
  • This antibody detects endogenous NAMPT.
  • Form:
  • Liquid
  • Isotype:
  • IgG2a
  • Recommend Usage:
  • Immunoprecipitation (1-2 ug/sample)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In 10 mM phosphate buffer, 150 mM NaCl, pH 7.5 (50% glycerol)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Publication Reference
  • Applications
  • Immunoprecipitation
  • Immunoprecipitation
  • IP-WB analysis of human NAMPT in cell lysates of three cell lines using this NAMPT monoclonal antibody, clone AF-1E12 (Cat # MAB8231) for IP and NAMPT polyclonal antibody (Cat # PAB17046) for WB.
    Lane 1, 2 : Raji
    Lane 3, 4 : HL-60
    Lane 5, 6 : K-562
  • ELISA
  • Application Image
  • ELISA
  • Gene Information
  • Gene Name:
  • NAMPT
  • Gene Alias:
  • 1110035O14Rik,DKFZp666B131,MGC117256,PBEF,PBEF1,VF,VISFATIN
  • Gene Description:
  • nicotinamide phosphoribosyltransferase
  • Gene Summary:
  • This gene encodes a protein that catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, one step in the biosynthesis of nicotinamide adenine dinucleotide. The protein is an adipokine that is localized to the bloodstream and has various functions, including the promotion of vascular smooth muscle cell maturation and inhibition of neutrophil apoptosis. It also activates insulin receptor and has insulin-mimetic effects, lowering blood glucose and improving insulin sensitivity. The protein is highly expressed in visceral fat and serum levels of the protein correlate with obesity. This gene has a pseudogene on chromosome 10. [provided by RefSeq
  • Other Designations:
  • NAmPRTase,pre-B cell-enhancing factor,pre-B-cell colony enhancing factor 1
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