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COBRA1 monoclonal antibody, clone F7E4 

  • Catalog # : MAB8174
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against full length recombinant COBRA1.
  • Immunogen:
  • Recombinant protein corresponding to full length human COBRA1.
  • Host:
  • Mouse
  • Theoretical MW (kDa):
  • 62
  • Reactivity:
  • Human, Mouse, Rat
  • Specificity:
  • This antibody has been directly tested for reactivity in Western blots with human, mouse and rat tissue. specific to the ~62k COBRA1 protein in Western blots of neonatal rat brain lysate.
  • Form:
  • Liquid
  • Purification:
  • Protein G purification
  • Isotype:
  • IgG1
  • Recommend Usage:
  • Western Blot (1:1000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.05% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • Western blot of neonatal rat brain lysate showing specific immunolabeling of the ~ 62K COBRA1 protein.
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • Gene Information
  • Gene Name:
  • COBRA1
  • Gene Alias:
  • DKFZp586B0519,KIAA1182,NELF-B,NELFB
  • Gene Description:
  • cofactor of BRCA1
  • Gene Summary:
  • NELFB is a subunit of negative elongation factor (NELF), which also includes NELFA (WHSC2; MIM 606026), either NELFC or NELFD (TH1L; MIM 605297), and NELFE (RDBP; MIM 154040). NELF acts with DRB sensitivity-inducing factor (DSIF), a heterodimer of SPT4 (SUPT4H1; MIM 603555) and SPT5 (SUPT5H; MIM 602102), to cause transcriptional pausing of RNA polymerase II (see MIM 180660) (Narita et al., 2003 [PubMed 12612062]).[supplied by OMIM
  • Other Designations:
  • negative elongation factor protein B
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