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Last updated: 2016/10/23
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CCL5 monoclonal antibody, clone 8.PP.11

  • Catalog # : MAB8063
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against CCL5.
  • Immunogen:
  • Human CCL5.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Isotype:
  • IgG2b
  • Recommend Usage:
  • ELISA (2-4 ug/mL)
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (5 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.2 (40% glycerol)
  • Storage Instruction:
  • Store at 4°C for three months. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) staining in human spleen tissue with CCL5 monoclonal antibody, clone 8.PP.11 (Cat # MAB8063).
  • Inhibition Assay
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Inhibition Assay
  • Gene Information
  • Entrez GeneID:
  • 6352
  • Gene Name:
  • CCL5
  • Gene Alias:
  • D17S136E,MGC17164,RANTES,SCYA5,SISd,TCP228
  • Gene Description:
  • chemokine (C-C motif) ligand 5
  • Gene Summary:
  • This gene is one of several CC cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene functions as a chemoattractant for blood monocytes, memory T helper cells and eosinophils. It causes the release of histamine from basophils and activates eosinophils. This cytokine is one of the major HIV-suppressive factors produced by CD8+ cells. It functions as one of the natural ligands for the chemokine receptor CCR5 and it suppresses in vitro replication of the R5 strains of HIV-1, which use CCR5 as a coreceptor. [provided by RefSeq
  • Other Designations:
  • SIS-delta,T-cell specific RANTES protein,T-cell specific protein p288,beta-chemokine RANTES,regulated upon activation, normally T-expressed, and presumably secreted,small inducible cytokine A5,small inducible cytokine A5 (RANTES),small inducible cytokine
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