Mouse monoclonal antibody raised against recombinant MAPK1.
Recombinant protein corresponding to human MAPK1.
Western Blot (1:500-1:2000) ELISA (1:10000-1:10000) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (5 ug/mL) Immunohistochemistry (Frozen sections) (1:500-1:2000) The optimal working dilution should be determined by the end user.
In PBS (0.01% sodium azide)
Store at 4°C for three months. For long term storage store at -20°C. Aliquot to avoid repeated freezing and thawing.
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene. [provided by RefSeq