LAMA5 monoclonal antibody, clone 4B12
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More Files
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Immunofluorescence
Immunofluorescence staining on human embryonic lung alveolae epithelium (A) and kidney (B) with LAMA5 monoclonal antibody, clone 4B12 (Cat # MAB7872).
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Specification
Product Description
Mouse monoclonal antibody raised against native LAMA5.
Immunogen
Laminin purified from human placenta.
Host
Mouse
Reactivity
Human
Form
Liquid
Purification
Protein G purification
Isotype
IgG1
Recommend Usage
ELISA (0.125 ug/mL)
Immunohistochemistry
Immunofluorescence
Immunoprecipitation (0.5 mgL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4 (0.09% sodium azide)
Storage Instruction
Store at -20°C. For long term storage store at -80°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry
Immunofluorescence
Immunofluorescence staining on human embryonic lung alveolae epithelium (A) and kidney (B) with LAMA5 monoclonal antibody, clone 4B12 (Cat # MAB7872).Immunoprecipitation
Enzyme-linked Immunoabsorbent Assay
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Gene Info — LAMA5
Entrez GeneID
3911Gene Name
LAMA5
Gene Alias
KIAA1907
Gene Description
laminin, alpha 5
Omim ID
601033Gene Ontology
HyperlinkGene Summary
Components of the extracellular matrix exert myriad effects on tissues throughout the body. In particular, the laminins, a family of heterotrimeric extracellular glycoproteins, affect tissue development and integrity in such diverse organs as the kidney, lung, skin, and nervous system. It is thought that laminins mediate the attachment, migration, and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Laminins function as heterotrimeric complexes of alpha, beta, and gamma chains, with each chain type representing a different subfamily of proteins. The protein encoded by this gene belongs to the alpha subfamily of laminin chains and is a major component of basement membranes. Two transcript variants encoding different isoforms have been found for this gene, but the full-length nature of one of them has not been determined. [provided by RefSeq
Other Designations
laminin alpha 5|laminin alpha-5 chain
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Interactome
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Pathway
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Disease
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