JUN (phospho T91/T93)monoclonal antibody, clone C-J 4C4/1
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Specification
Product Description
Mouse monoclonal antibody raised against phosphorylated JUN.
Immunogen
Human/Rat JUN phosphorylated at T91 and T93.
Host
Mouse
Reactivity
Human, Rat
Specificity
This recognizes c-Jun phosphorylated at T91 and T93, or just at T91 but not at T93 alone. Not yet tested in other species. Predicted molecular weight: 36 KDa. Not tested in other applications.
Form
Liquid
Isotype
IgG1
Recommend Usage
The optimal working dilution should be determined by the end user.
Storage Buffer
In PBS
Storage Instruction
Store at 4°C for short term. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Western Blot
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Gene Info — JUN
Entrez GeneID
3725Gene Name
JUN
Gene Alias
AP-1, AP1, c-Jun
Gene Description
jun oncogene
Omim ID
165160Gene Ontology
HyperlinkGene Summary
This gene is the putative transforming gene of avian sarcoma virus 17. It encodes a protein which is highly similar to the viral protein, and which interacts directly with specific target DNA sequences to regulate gene expression. This gene is intronless and is mapped to 1p32-p31, a chromosomal region involved in both translocations and deletions in human malignancies. [provided by RefSeq
Other Designations
Jun activation domain binding protein|OTTHUMP00000010036|activator protein 1|enhancer-binding protein AP1|v-jun avian sarcoma virus 17 oncogene homolog|v-jun sarcoma virus 17 oncogene homolog
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Gene Info — Jun
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Interactome
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Pathway
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Disease
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Publication Reference
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The ubiquitin ligase SCFFbw7 antagonizes apoptotic JNK signaling.
Nateri AS, Riera-Sans L, Da Costa C, Behrens A.
Science 2004 Feb; 303(5662):1374.
Application:WB-Tr, Human, HEK 293T, PC12 cells.
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The ubiquitin ligase SCFFbw7 antagonizes apoptotic JNK signaling.
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