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Last updated: 2017/12/10
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FAT1 monoclonal antibody, clone Fat-1

  • Catalog # : MAB7207
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against FAT1.
  • Immunogen:
  • Cytoplasmic domain of drosphila FAT1.
  • Host:
  • Mouse
  • Reactivity:
  • Fruit fly
  • Specificity:
  • FAT (Fat-1). Expected to cross-react with Rat (85% identity with immunogen) and Chimpanzee (92% identity with immunogen) due to sequence homology. Predicted molecular weight 506 KDa.
  • Form:
  • Liquid
  • Isotype:
  • IgM
  • Recommend Usage:
  • The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS
  • Storage Instruction:
  • Store at 4°C for short term. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Publication Reference
  • Applications
  • Western Blot
  • Immunofluorescence
  • Application Image
  • Western Blot
  • Immunofluorescence
  • Gene Information
  • Entrez GeneID:
  • 2195
  • Gene Name:
  • FAT1
  • Gene Alias:
  • CDHF7,FAT,ME5,hFat1
  • Gene Description:
  • FAT tumor suppressor homolog 1 (Drosophila)
  • Gene Summary:
  • This gene is an ortholog of the Drosophila fat gene, which encodes a tumor suppressor essential for controlling cell proliferation during Drosophila development. The gene product is a member of the cadherin superfamily, a group of integral membrane proteins characterized by the presence of cadherin-type repeats. In addition to containing 34 tandem cadherin-type repeats, the gene product has five epidermal growth factor (EGF)-like repeats and one laminin A-G domain. This gene is expressed at high levels in a number of fetal epithelia. Its product probably functions as an adhesion molecule and/or signaling receptor, and is likely to be important in developmental processes and cell communication. Transcript variants derived from alternative splicing and/or alternative promoter usage exist, but they have not been fully described. [provided by RefSeq
  • Other Designations:
  • FAT tumor suppressor 1,cadherin ME5,cadherin family member 7,cadherin-related tumor suppressor
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