FGF3 monoclonal antibody, clone MSD1
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Specification
Product Description
Mouse monoclonal antibody raised against synthetic peptide of FGF3.
Immunogen
A synthetic peptide (conjugated with BSA) corresponding to human FGF3.
Sequence
RRTQKSSLFLPRVL
Host
Mouse
Reactivity
Human, Mouse, Xenopus
Specificity
Detects a band at 27 KDa.
Form
Liquid
Isotype
IgG2a
Recommend Usage
The optimal working dilution should be determined by the end user.
Storage Buffer
In PBS
Storage Instruction
Store at -20°C or -80°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Western Blot
Immunohistochemistry
Immunocytochemistry
Immunofluorescence
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Gene Info — FGF3
Entrez GeneID
2248Gene Name
FGF3
Gene Alias
HBGF-3, INT2
Gene Description
fibroblast growth factor 3 (murine mammary tumor virus integration site (v-int-2) oncogene homolog)
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene was identified by its similarity with mouse fgf3/int-2, a proto-oncogene activated in virally induced mammary tumors in the mouse. Frequent amplification of this gene has been found in human tumors, which may be important for neoplastic transformation and tumor progression. Studies of the similar genes in mouse and chicken suggested the role in inner ear formation. [provided by RefSeq
Other Designations
INT-2 proto-oncogene protein|V-INT2 murine mammary tumor virus integration site oncogene homolog|fibroblast growth factor 3|murine mammary tumor virus integration site 2, mouse|oncogene INT2
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Interactome
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Pathway
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Publication Reference
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DEC1 (STRA13) protein expression relates to hypoxia- inducible factor 1-alpha and carbonic anhydrase-9 overexpression in non-small cell lung cancer.
Giatromanolaki A, Koukourakis MI, Sivridis E, Turley H, Wykoff CC, Gatter KC, Harris AL.
The Journal of Pathology 2003 Jun; 200(2):222.
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DEC1 (STRA13) protein expression relates to hypoxia- inducible factor 1-alpha and carbonic anhydrase-9 overexpression in non-small cell lung cancer.
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