ICOSLG monoclonal antibody, clone ANC4E3
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Specification
Product Description
Mouse monoclonal antibody raised against ICOSLG.
Immunogen
A mixture of human Raji cells and recombinant human ICOSLG-muIg.
Host
Mouse
Reactivity
Human
Form
Liquid
Isotype
IgG1, kappa
Recommend Usage
The optimal working dilution should be determined by the end user.
Storage Buffer
In 50 mM sodium phosphate buffer, 100 mM potassium Chloride, 150 mM NaCl, pH 7.5 (0.5 mg/mL gentamicin sulfate)
Storage Instruction
Store at 4°C.
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Applications
Enzyme Immunoassay
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Gene Info — ICOSLG
Entrez GeneID
23308Gene Name
ICOSLG
Gene Alias
B7-H2, B7H2, B7RP-1, B7RP1, CD275, GL50, ICOS-L, ICOSL, KIAA0653, LICOS
Gene Description
inducible T-cell co-stimulator ligand
Omim ID
605717Gene Ontology
HyperlinkOther Designations
B7-like protein|OTTHUMP00000109524|transmembrane protein B7-H2 ICOS ligand
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Interactome
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Pathway
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Disease
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Publication Reference
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Importance of ICOS-B7RP-1 costimulation in acute and chronic allograft rejection.
Ozkaynak E, Gao W, Shemmeri N, Wang C, Gutierrez-Ramos JC, Amaral J, Qin S, Rottman JB, Coyle AJ, Hancock WW.
Nature Immunology 2001 Jul; 2(7):591.
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The costimulatory molecule ICOS plays an important role in the immunopathogenesis of EAE.
Rottman JB, Smith T, Tonra JR, Ganley K, Bloom T, Silva R, Pierce B, Gutierrez-Ramos JC, Ozkaynak E, Coyle AJ.
Nat Immunol 2001 Jul; 2(7):605.
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Differential expression of inducible costimulator-ligand splice variants: lymphoid regulation of mouse GL50-B and human GL50 molecules.
Ling V, Wu PW, Miyashiro JS, Marusic S, Finnerty HF, Collins M.
The Journal of Immunology 2001 Jun; 166(12):7300.
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Importance of ICOS-B7RP-1 costimulation in acute and chronic allograft rejection.
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