SLC3A2 monoclonal antibody, clone UM7F8
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Specification
Product Description
Mouse monoclonal antibody raised against native SLC3A2.
Immunogen
Native purified SLC3A2 from Molt 13 T cell line.
Host
Mouse
Reactivity
Human
Specificity
Antibody UM7F8 is comitogenic with soluble anti-CD2 and immobilized anti-CD3 mAbs.
Form
Liquid
Isotype
IgG1
Recommend Usage
The optimal working dilution should be determined by the end user.
Storage Buffer
In 50 mM sodium phosphate buffer, 100 mM potassium Chloride, 150 mM NaCl, pH 7.5 (0.5 mg/mL gentamicin sulfate)
Storage Instruction
Store at 4°C.
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Applications
Immunohistochemistry (Frozen sections)
Immunoprecipitation
Flow Cytometry
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Gene Info — SLC3A2
Entrez GeneID
6520Gene Name
SLC3A2
Gene Alias
4F2, 4F2HC, 4T2HC, CD98, CD98HC, MDU1, NACAE
Gene Description
solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2
Omim ID
158070Gene Ontology
HyperlinkGene Summary
This gene is a member of the solute carrier family and encodes a cell surface, transmembrane protein with an alpha amylase domain. The protein exists as the heavy chain of a heterodimer, covalently bound through di-sulfide bonds to one of several possible light chains. It associates with integrins and mediates integrin-dependent signaling related to normal cell growth and tumorigenesis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq
Other Designations
4F2 cell-surface antigen heavy chain|4F2 heavy chain|CD98 heavy chain|antigen defined by monoclonal antibody 4F2, heavy chain|antigen identified by monoclonal antibodies 4F2, TRA1.10, TROP4, and T43|heavy chain|lymphocyte activation antigen 4F2 large subu
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Interactome
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Disease
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Publication Reference
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The human 4F2 antigen: evidence for cryptic and noncryptic epitopes and for a role of 4F2 in human T lymphocyte activation.
Freidman AW, Diaz LA Jr, Moore S, Schaller J, Fox DA.
Cellular Immunology 1994 Apr; 154(1):253.
Application：Flow Cyt, Human, Mouse, Fibroblasts, PBMC.
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The human 4F2 antigen: evidence for cryptic and noncryptic epitopes and for a role of 4F2 in human T lymphocyte activation.
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