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SELP monoclonal antibody, clone G1/G1-4

  • Catalog # : MAB6958
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against native SELP.
  • Immunogen:
  • Native purified SELP from purified human platelet.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Specificity:
  • Antibody G1 blocks the activated endothelium or platelet-neutrophil interaction.
  • Form:
  • Liquid
  • Isotype:
  • IgG1
  • Recommend Usage:
  • The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In 50 mM sodium phosphate buffer, 100 mM potassium Chloride, 150 mM NaCl, pH 7.5 (0.5 mg/mL gentamicin sulfate)
  • Storage Instruction:
  • Store at 4°C.
  • Publication Reference
  • Applications
  • Immunohistochemistry (Frozen sections)
  • Immunoprecipitation
  • Flow Cytometry
  • Application Image
  • Immunohistochemistry (Frozen sections)
  • Immunoprecipitation
  • Flow Cytometry
  • Gene Information
  • Entrez GeneID:
  • 6403
  • Gene Name:
  • SELP
  • Gene Alias:
  • CD62,CD62P,FLJ45155,GMP140,GRMP,LECAM3,PADGEM,PSEL
  • Gene Description:
  • selectin P (granule membrane protein 140kDa, antigen CD62)
  • Gene Summary:
  • This gene encodes a 140 kDa protein that is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. This protein redistributes to the plasma membrane during platelet activation and degranulation and mediates the interaction of activated endothelial cells or platelets with leukocytes. The membrane protein is a calcium-dependent receptor that binds to sialylated forms of Lewis blood group carbohydrate antigens on neutrophils and monocytes. Alternative splice variants may occur but are not well documented. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000032609,antigen CD62,granulocyte membrane protein,leukocyte-endothelial cell adhesion molecule 3,platelet alpha-granule membrane protein,selectin P,selectin P (granule membrane protein 140kD, antigen CD62)
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