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SELE monoclonal antibody, clone HAE-1f

  • Catalog # : MAB6956
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against native SELE.
  • Immunogen:
  • Native purified SELE from TNF activated HUVEC.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Specificity:
  • Antibody HAE-1f blocks the function of CD62E.
  • Form:
  • Liquid
  • Isotype:
  • IgG1
  • Recommend Usage:
  • The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In 50 mM sodium phosphate buffer, 100 mM potassium Chloride, 150 mM NaCl, pH 7.5 (0.5 mg/mL gentamicin sulfate)
  • Storage Instruction:
  • Store at 4°C.
  • Publication Reference
  • Applications
  • Immunohistochemistry (Frozen sections)
  • Immunoprecipitation
  • Flow Cytometry
  • Application Image
  • Immunohistochemistry (Frozen sections)
  • Immunoprecipitation
  • Flow Cytometry
  • Gene Information
  • Entrez GeneID:
  • 6401
  • Gene Name:
  • SELE
  • Gene Alias:
  • CD62E,ELAM,ELAM1,ESEL,LECAM2
  • Gene Description:
  • selectin E
  • Gene Summary:
  • The protein encoded by this gene is found in cytokine-stimulated endothelial cells and is thought to be responsible for the accumulation of blood leukocytes at sites of inflammation by mediating the adhesion of cells to the vascular lining. It exhibits structural features such as the presence of lectin- and EGF-like domains followed by short consensus repeat (SCR) domains that contain 6 conserved cysteine residues. These proteins are part of the selectin family of cell adhesion molecules. Adhesion molecules participate in the interaction between leukocytes and the endothelium and appear to be involved in the pathogenesis of atherosclerosis. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000032745,endothelial adhesion molecule 1,leukocyte endothelial cell adhesion molecule 2
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