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Last updated: 2016/12/4
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ITGB4 monoclonal antibody, clone UMA9

  • Catalog # : MAB6946
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against native ITGB4.
  • Immunogen:
  • Native purified ITGB4 from human squamous cell carcinoma (UM-SCC-1).
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Specificity:
  • Partially blocks laminin binding.
  • Form:
  • Liquid
  • Isotype:
  • IgG2a
  • Recommend Usage:
  • The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In 50 mM sodium phosphate buffer, 100 mM potassium Chloride, 150 mM NaCl, pH 7.5 (0.5 mg/mL gentamicin sulfate)
  • Storage Instruction:
  • Store at 4°C.
  • Publication Reference
  • Applications
  • Western Blot
  • Immunohistochemistry (Frozen sections)
  • Immunoprecipitation
  • Flow Cytometry
  • Application Image
  • Western Blot
  • Immunohistochemistry (Frozen sections)
  • Immunoprecipitation
  • Flow Cytometry
  • Gene Information
  • Entrez GeneID:
  • 3691
  • Gene Name:
  • ITGB4
  • Gene Alias:
  • CD104
  • Gene Description:
  • integrin, beta 4
  • Gene Summary:
  • Integrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta 4 subunit, a receptor for the laminins. This subunit tends to associate with alpha 6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • CD104 antigen,GP150,integrin beta 4,integrin beta-4 subunit
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