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Last updated: 2016/11/27
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IL2RB monoclonal antibody, clone 9A2 (DU-2)

  • Catalog # : MAB6937
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against native IL2RB.
  • Immunogen:
  • Native purified IL2RB from YT-1 acute human leukemia cells.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Specificity:
  • Antibody 9A2 (DU-2) inhibits binding of IL-2 to IL-2R beta (CD122).
  • Form:
  • Liquid
  • Isotype:
  • IgG2a, kappa
  • Recommend Usage:
  • The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In 50 mM sodium phosphate buffer, 100 mM potassium Chloride, 150 mM NaCl, pH 7.5 (0.5 mg/mL gentamicin sulfate)
  • Storage Instruction:
  • Store at 4°C.
  • Publication Reference
  • Applications
  • Immunohistochemistry (Frozen sections)
  • Immunoprecipitation
  • Flow Cytometry
  • Application Image
  • Immunohistochemistry (Frozen sections)
  • Immunoprecipitation
  • Flow Cytometry
  • Gene Information
  • Entrez GeneID:
  • 3560
  • Gene Name:
  • IL2RB
  • Gene Alias:
  • CD122,P70-75
  • Gene Description:
  • interleukin 2 receptor, beta
  • Gene Summary:
  • The interleukin 2 receptor, which is involved in T cell-mediated immune responses, is present in 3 forms with respect to ability to bind interleukin 2. The low affinity form is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha/beta subunit heterodimer, while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer. Both the intermediate and high affinity forms of the receptor are involved in receptor-mediated endocytosis and transduction of mitogenic signals from interleukin 2. The protein encoded by this gene represents the beta subunit and is a type I membrane protein. [provided by RefSeq
  • Other Designations:
  • CD122 antigen,OTTHUMP00000028799,high affinity IL-2 receptor beta subunit,interleukin 2 receptor beta
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