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Last updated: 2017/11/19
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GYPA monoclonal antibody, clone A63-B/C2

  • Catalog # : MAB6932
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against native GYPA.
  • Immunogen:
  • Native purified GYPA from neuraminidase treated human erythrocytes.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Isotype:
  • IgM
  • Recommend Usage:
  • The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In 50 mM sodium phosphate buffer, 100 mM potassium Chloride, 150 mM NaCl, pH 7.5 (0.5 mg/mL gentamicin sulfate)
  • Storage Instruction:
  • Store at 4°C.
  • Publication Reference
  • Applications
  • Flow Cytometry
  • Flow Cytometry
  • 107 human red blood cells were washed and preincubated 5 minutes with 20 uL of 250 ug/mL human IgG (to block non specific binding) after which they were incubated 45 minutes on ice with 80ul of anti-CD235a (Glycophorin A) /Biotin at 20 ug/mL. Cells were washed twice and incubated with Streptavidin/R-Phycoerythrin, after which they were washed three times, fixed and analyzed by FACS. Cells stained positive with a mean shift of 2.27 log10 fluorescent units when compared to a Mouse IgM/Biotin negative control at a similar concentration. Binding was 82% blocked when pre incubated 10 minutes with 20 uL of 0.5 mg/mL GYPA monoclonal antibody, clone A63-B/C2 (Cat # MAB6932).
  • Application Image
  • Gene Information
  • Entrez GeneID:
  • 2993
  • Gene Name:
  • GYPA
  • Gene Alias:
  • CD235a,GPA,GPErik,GPSAT,GpMiIII,HGpMiIII,HGpMiV,HGpMiX,HGpMiXI,HGpSta(C),MN,MNS
  • Gene Description:
  • glycophorin A (MNS blood group)
  • Gene Summary:
  • Glycophorins A (GYPA) and B (GYPB) are major sialoglycoproteins of the human erythrocyte membrane which bear the antigenic determinants for the MN and Ss blood groups. In addition to the M or N and S or s antigens that commonly occur in all populations, about 40 related variant phenotypes have been identified. These variants include all the variants of the Miltenberger complex and several isoforms of Sta, as well as Dantu, Sat, He, Mg, and deletion variants Ena, S-s-U- and Mk. Most of the variants are the result of gene recombinations between GYPA and GYPB. [provided by RefSeq
  • Other Designations:
  • Mi.V glycoprotein (24 AA),erythroid-lineage-specific membrane sialoglycoprotein,glycophorin A,glycophorin A (MN blood group),glycophorin A MNS blood group,glycophorin A, GPA,glycophorin Erik,glycophorin MiI,glycophorin MiIII,glycophorin MiV,glycophorin Mi
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