CR2 monoclonal antibody, clone BU33
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Specification
Product Description
Mouse monoclonal antibody raised against native CR2.
Immunogen
Native purified CR2 from Human HFB-1 cell line.
Host
Mouse
Theoretical MW (kDa)
145
Reactivity
Human
Specificity
This antibody recognizes CR2.
Form
Liquid
Isotype
IgG1
Recommend Usage
The optimal working dilution should be determined by the end user.
Storage Buffer
In 50 mM sodium phosphate buffer, 100 mM potassium Chloride, 150 mM NaCl, pH 7.5 (0.5 mg/mL gentamicin sulfate)
Storage Instruction
Store at 4°C.
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Applications
Immunohistochemistry (Frozen sections)
Immunoprecipitation
Flow Cytometry
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Gene Info — CR2
Entrez GeneID
1380Gene Name
CR2
Gene Alias
C3DR, CD21, SLEB9
Gene Description
complement component (3d/Epstein Barr virus) receptor 2
Gene Ontology
HyperlinkGene Summary
Complement component receptor-2 (CR2) is the membrane protein on B lymphocytes to which the Epstein-Barr virus (EBV) binds during infection of these cells. See also CR1 (MIM 120620). Yefenof et al. (1976) [PubMed 181330] found complete overlapping of EBV receptors and C3 (MIM 120700) receptors on human B lymphocytes.[supplied by OMIM
Other Designations
OTTHUMP00000034421|OTTHUMP00000034447
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Interactome
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Pathway
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Disease
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Publication Reference
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Epstein-Barr virus modulates de novo protein synthesis in human neutrophils.
Beaulieu AD, Paquin R, Gosselin J.
Blood 1995 Oct; 86(7):2789.
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Characterization of a complement receptor 2 (CR2, CD21) ligand binding site for C3. An initial model of ligand interaction with two linked short consensus repeat modules.
Molina H, Perkins SJ, Guthridge J, Gorka J, Kinoshita T, Holers VM.
Journal of Immunology 1995 May; 154(10):5426.
Application:Flow Cyt, Human, K-562 cells.
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Epstein-Barr virus modulates de novo protein synthesis in human neutrophils.
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