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Last updated: 2016/12/4
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CD53 monoclonal antibody, clone 63.5A3

  • Catalog # : MAB6916
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against native CD53.
  • Immunogen:
  • Native purified CD53 from human sezary cells.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Isotype:
  • IgG2b
  • Recommend Usage:
  • The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In 50 mM sodium phosphate buffer, 100 mM potassium Chloride, 150 mM NaCl, pH 7.5 (0.5 mg/mL gentamicin sulfate)
  • Storage Instruction:
  • Store at 4°C.
  • Applications
  • Immunohistochemistry (Frozen sections)
  • Immunoprecipitation
  • Flow Cytometry
  • Application Image
  • Immunohistochemistry (Frozen sections)
  • Immunoprecipitation
  • Flow Cytometry
  • Gene Information
  • Entrez GeneID:
  • 963
  • Gene Name:
  • CD53
  • Gene Alias:
  • MOX44,TSPAN25
  • Gene Description:
  • CD53 molecule
  • Gene Summary:
  • The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. It contributes to the transduction of CD2-generated signals in T cells and natural killer cells and has been suggested to play a role in growth regulation. Familial deficiency of this gene has been linked to an immunodeficiency associated with recurrent infectious diseases caused by bacteria, fungi and viruses. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq
  • Other Designations:
  • CD53 antigen,CD53 glycoprotein,CD53 tetraspan antigen,OTTHUMP00000013686,OTTHUMP00000059505,antigen MOX44 identified by monoclonal antibody MRC-OX44,cell surface antigen,leukocyte surface antigen CD53,tetraspanin-25,transmembrane glycoprotein
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