CD44 monoclonal antibody, clone BU52
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
-
Specification
Product Description
Mouse monoclonal antibody raised against CD44.
Immunogen
Native purified CD44 from human peripheral myeloma cells.
Host
Mouse
Reactivity
Human
Form
Liquid
Isotype
IgG1
Recommend Usage
The optimal working dilution should be determined by the end user.
Storage Buffer
In 50 mM sodium phosphate buffer, 100 mM potassium Chloride, 150 mM NaCl, pH 7.5 (0.5 mg/mL gentamicin sulfate)
Storage Instruction
Store at 4°C.
-
Applications
Immunohistochemistry (Frozen sections)
Immunoprecipitation
Flow Cytometry
-
Gene Info — CD44
Entrez GeneID
960Gene Name
CD44
Gene Alias
CDW44, CSPG8, ECMR-III, HCELL, IN, LHR, MC56, MDU2, MDU3, MGC10468, MIC4, MUTCH-I, Pgp1
Gene Description
CD44 molecule (Indian blood group)
Omim ID
107269Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis. [provided by RefSeq
Other Designations
CD44 antigen|CD44 antigen (homing function and Indian blood group system)|CDW44 antigen|GP90 lymphocyte homing/adhesion receptor|Hermes antigen|antigen gp90 homing receptor|cell adhesion molecule|cell surface glycoprotein CD44|chondroitin sulfate proteogl
-
Interactome
-
Pathway
-
Disease
-
Publication Reference
-
N-terminal and central regions of the human CD44 extracellular domain participate in cell surface hyaluronan binding.
Liao HX, Lee DM, Levesque MC, Haynes BF.
Journal of Immunology 1995 Oct; 155(8):3938.
Application:Flow Cyt, IA, WB-Tr, Human, Monkey, 26CB-1 baboon, COS, Jurkat cells.
-
CD44 and its interaction with extracellular matrix.
Lesley J, Hyman R, Kincade PW.
Advances in Immunology 1993 Mar; 54:271.
-
New monoclonal antibodies in CD44 and CD58: their use to quantify CD44 and CD58 on normal human erythrocytes and to compare the distribution of CD44 and CD58 in human tissues.
Anstee DJ, Gardner B, Spring FA, Holmes CH, Simpson KL, Parsons SF, Mallinson G, Yousaf SM, Judson PA.
Immunology 1991 Oct; 74(2):197.
Application:IA, Human, Human erythrocytes, Human T cells.
-
N-terminal and central regions of the human CD44 extracellular domain participate in cell surface hyaluronan binding.
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com