ALCAM monoclonal antibody, clone 3A6
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against ALCAM.
Immunogen
Native from human thymic epithelial cells.
Host
Mouse
Reactivity
Human
Specificity
This antibody blocks binding of CD6 to CD166.
Form
Liquid
Isotype
IgG1
Recommend Usage
The optimal working dilution should be determined by the end user.
Storage Buffer
In 50 mM sodium phosphate buffer, 100 mM potassium Chloride, 150 mM NaCl, pH 7.5 (0.5 mg/mL gentamicin sulfate)
Storage Instruction
Store at 4°C.
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Applications
Immunohistochemistry (Frozen sections)
Immunoprecipitation
Flow Cytometry
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Gene Info — ALCAM
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Interactome
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Pathway
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Disease
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Publication Reference
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Mesenchymal stem cell-natural killer cell interactions: evidence that activated NK cells are capable of killing MSCs, whereas MSCs can inhibit IL-2-induced NK-cell proliferation.
Spaggiari GM, Capobianco A, Becchetti S, Mingari MC, Moretta L.
Blood 2006 Feb; 107(4):1484.
Application:Flow Cyt, Human, Human mesenchymal stem cells.
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The amino-terminal immunoglobulin-like domain of activated leukocyte cell adhesion molecule binds specifically to the membrane-proximal scavenger receptor cysteine-rich domain of CD6 with a 1:1 stoichiometry.
Bowen MA, Bajorath J, Siadak AW, Modrell B, Malacko AR, Marquardt H, Nadler SG, Aruffo A.
The Journal of Biological Chemistry 1996 Jul; 271(29):17390.
Application:ELISA, Flow Cyt, Human, Monkey, COS cells, HPB-ALL cells, Recombinant proteins.
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Cloning, mapping, and characterization of activated leukocyte-cell adhesion molecule (ALCAM), a CD6 ligand.
Bowen MA, Patel DD, Li X, Modrell B, Malacko AR, Wang WC, Marquardt H, Neubauer M, Pesando JM, Francke U, et al..
The Journal of Experimental Medicine 1995 Jun; 181(6):2213.
Application:Flow Cyt, Human, Monkey, COS cells, PBMCs, T cells.
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Mesenchymal stem cell-natural killer cell interactions: evidence that activated NK cells are capable of killing MSCs, whereas MSCs can inhibit IL-2-induced NK-cell proliferation.
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