TFRC/TFR2 monoclonal antibody, clone CY-TFR
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against TFRC/TFR2.
Immunogen
Purified human TFRC/TFR2.
Host
Mouse
Reactivity
Human
Specificity
This antibody react with human Transferrin Receptor.
Form
Lyophilized
Isotype
IgG1, kappa
Recommend Usage
The optimal working dilution should be determined by the end user.
Storage Buffer
Lyophilized from 10 mM PBS, pH 7.2
Storage Instruction
Store at -20°C.
Aliquot after reconstitution to avoid repeated freezing and thawing. -
Applications
Enzyme-linked Immunoabsorbent Assay
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Gene Info — TFR2
Entrez GeneID
7036Gene Name
TFR2
Gene Alias
HFE3, MGC126368, TFRC2
Gene Description
transferrin receptor 2
Gene Ontology
HyperlinkGene Summary
This gene is a member of the transferrin receptor-like family and encodes a single-pass type II membrane protein with a protease associated (PA) domain, an M28 peptidase domain and a transferrin receptor-like dimerization domain. This protein mediates cellular uptake of transferrin-bound iron and mutations in this gene have been associated with hereditary hemochromatosis type III. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq
Other Designations
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Gene Info — TFRC
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Interactome
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Pathway
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Disease
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Publication Reference
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Insulin-induced exocytosis regulates the cell surface level of low density lipoprotein-related protein-1 in Müller Glial cells.
Actis Dato V, Grosso RA, Sánchez MC, Fader CM, Chiabrando GA.
The Biochemical Journal 2018 May; 475(9):1669.
Application：WB , Human, MIO-M1 cells.
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Insulin-induced exocytosis regulates the cell surface level of low density lipoprotein-related protein-1 in Müller Glial cells.
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