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Last updated: 2016/12/4
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ABCC12 monoclonal antibody, clone M9II-3

  • Catalog # : MAB6675
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  • Specification
  • Product Description:
  • Rat monoclonal antibody raised against partial recombinant ABCC12.
  • Immunogen:
  • Recombinant protein corresponding to amino acids 690-734 of human ABCC12.
  • Host:
  • Rat
  • Reactivity:
  • Human
  • Specificity:
  • M9II-3 reacts with an internal epitope of MRP9 (ABCC12), an approximately 150 kD transmembrane protein that is related to the multidrug resistance protein MRP1
  • Form:
  • Liquid
  • Isotype:
  • IgG
  • Recommend Usage:
  • Immunohistochemistry (Frozen sections) (1:20)
    Immunocytochemistry (1:20-1:50)
    Wstern Blot (1:20-1:50)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In serum-free culture supernatant (0.7% BSA, 0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • 1.
  • Multidrug resistance-associated protein 9 (ABCC12) is present in mouse and boar sperm.
    Ono N, Van der Heijden I, Scheffer GL, Van de Wetering K, Van Deemter E, De Haas M, Boerke A, Gadella BM, De Rooij DG, Neefjes JJ, Groothuis TA, Oomen L, Brocks L, Ishikawa T, Borst P.Ono N, Van der Heijden I, Scheffer GL, Van de Wetering K, Van Deemter E, De Haas M, Boerke A, Gadella BM, De Rooij DG, Neefjes JJ, Groothuis TA, Oomen L, Brocks L, Ishikawa T, Borst P.
  • 2.
  • ABCC10, ABCC11, and ABCC12.
    Kruh GD, Guo Y, Hopper-Borge E, Belinsky MG, Chen ZS.Kruh GD, Guo Y, Hopper-Borge E, Belinsky MG, Chen ZS.
  • Applications
  • Western Blot
  • Immunohistochemistry (Frozen sections)
  • Immunocytochemistry
  • Application Image
  • Western Blot
  • Immunohistochemistry (Frozen sections)
  • Immunocytochemistry
  • Gene Information
  • Gene Name:
  • ABCC12
  • Gene Alias:
  • MGC27071,MRP9
  • Gene Description:
  • ATP-binding cassette, sub-family C (CFTR/MRP), member 12
  • Gene Summary:
  • This gene is a member of the superfamily of ATP-binding cassette (ABC) transporters and the encoded protein contains two ATP-binding domains and 12 transmembrane regions. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies: ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White. This gene is a member of the MRP subfamily which is involved in multi-drug resistance. This gene and another subfamily member are arranged head-to-tail on chromosome 16q12.1. Increased expression of this gene is associated with breast cancer. [provided by RefSeq
  • Other Designations:
  • ATP-binding cassette protein C12,ATP-binding cassette transporter sub-family C member 12,OTTHUMP00000164186,multidrug resistance-associated protein 9
  • Gene Pathway
  • Related Disease
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