Ahsa1 monoclonal antibody, clone 25F2.D10
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Specification
Product Description
Rat monoclonal antibody raised against Ahsa1.
Immunogen
Mouse Aha1.
Host
Rat
Reactivity
Human, Mouse, Rat
Specificity
Approximately 38 KDa, can run at up to 45 KDa on SDS-PAGE.
Form
Liquid
Isotype
IgG2a, kappa
Recommend Usage
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In 20 mM potassium phosphate buffer, 150 mM NaCl, pH 7.2
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Western Blot
Immunohistochemistry
Immunocytochemistry
Immunofluorescence
Immunoprecipitation
Enzyme-linked Immunoabsorbent Assay
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Gene Info — Ahsa1
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Publication Reference
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The charged linker region is an important regulator of Hsp90 function.
Hainzl O, Lapina MC, Buchner J, Richter K.
The Journal of Biological Chemistry 2009 Jun; 284(34):22559.
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Silencing of HSP90 cochaperone AHA1 expression decreases client protein activation and increases cellular sensitivity to the HSP90 inhibitor 17-allylamino-17-demethoxygeldanamycin.
Holmes JL, Sharp SY, Hobbs S, Workman P.
Cancer Research 2008 Feb; 68(4):1188.
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A novel HSP90 chaperone complex regulates intracellular vesicle transport.
Lotz GP, Brychzy A, Heinz S, Obermann WM.
Journal of Cell Science 2008 Feb; 121(Pt 5):717.
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The charged linker region is an important regulator of Hsp90 function.
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