Hcn4 monoclonal antibody, clone N114/10
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More Files
- More Functions
Western Blot (Transfected lysate)
Western blot analysis in Hcn4 transfected HEK cell with Hcn4 monoclonal antibody, clone N114/10 (Cat # MAB6667).
Immunofluorescence
Immunofluorescence staining in human hippocampus with Hcn4 monoclonal antibody, clone N114/10 (Cat # MAB6667).
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Specifications
Product Description
Mouse monoclonal antibody raised against partial recombinant Hcn4.
Immunogen
Recombinant fusion protein corresponding to C-terminus amino acids 1019-1198 of rat Hcn4.
Host
Mouse
Reactivity
Human, Mouse, Rat
Specificity
Detects ~130KDa. No cross-reactivity against other HCNs.
Form
Liquid
Isotype
IgG1
Recommend Usage
Western Blot (1:1000)
Immunohistochemistry (1:1000)
Immunocytochemistry (1:100)
Immunofluorescence (1:100)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4 (50% glycerol, 0.09% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Transfected lysate)
Western blot analysis in Hcn4 transfected HEK cell with Hcn4 monoclonal antibody, clone N114/10 (Cat # MAB6667).Immunohistochemistry
Immunocytochemistry
Immunofluorescence
Immunofluorescence staining in human hippocampus with Hcn4 monoclonal antibody, clone N114/10 (Cat # MAB6667). -
Gene Info — Hcn4
Entrez GeneID
59266Protein Accession#
Q9JKA7Gene Name
Hcn4
Gene Alias
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Gene Description
hyperpolarization activated cyclic nucleotide-gated potassium channel 4
Gene Ontology
HyperlinkGene Summary
cyclic nucleotide-gated K+ 4|hyperpolarization-activated
Other Designations
hyperpolarization-activated cyclic nucleotide-gated potassium channel 4 (HCN4)|hyperpolarization-activated, cyclic nucleotide-gated K+ 4|hyperpolarization-activated, cyclic nucleotide-gated potassium channel 4 (HCN4)
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Publication Reference
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Congenital long QT syndrome.
Crotti L, Celano G, Dagradi F, Schwartz PJ.
Orphanet Journal of Rare Diseases 2008 Jul; 3:18.
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Ca(V)1.2 calcium channel dysfunction causes a multisystem disorder including arrhythmia and autism.
Splawski I, Timothy KW, Sharpe LM, Decher N, Kumar P, Bloise R, Napolitano C, Schwartz PJ, Joseph RM, Condouris K, Tager-Flusberg H, Priori SG, Sanguinetti MC, Keating MT.
Cell 2004 Oct; 119(1):19.
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Congenital long QT syndrome.
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