Trpv3 monoclonal antibody, clone S15-4
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Specification
Product Description
Mouse monoclonal antibody raised against synthetic peptide of Trpv3.
Immunogen
A synthetic peptide corresponding to amino acids 458-474 (C-terminus) of rat Trpv3.
Host
Mouse
Reactivity
Human, Mouse, Rat
Specificity
Detects ~70KDa.
Form
Liquid
Isotype
IgG2a
Recommend Usage
Western Blot (1-10 ug/mL)
Immunohistochemistry (0.1-1.0 ug/mL)
Immunocytochemistry (0.1-1.0 ug/mL)
Immunofluorescence (1.0-10 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4 (50% glycerol, 0.09% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of human cell line mixed lysate with Trpv3 monoclonal antibody, clone S15-4 (Cat # MAB6666).Immunocytochemistry
Immunofluorescence
Immunofluorescence staining in human hippocampus with Trpv3 monoclonal antibody, clone S15-4 (Cat # MAB6666).Immunoprecipitation
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Gene Info — Trpv3
Entrez GeneID
497948Protein Accession#
NP_001020928Gene Name
Trpv3
Gene Alias
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Gene Description
transient receptor potential cation channel, subfamily V, member 3
Gene Ontology
HyperlinkGene Summary
subfamily V
Other Designations
heat sensitive channel TRPV3
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Publication Reference
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Spontaneous Calcium Transients in Human Neural Progenitor Cells Mediated by Transient Receptor Potential Channels.
Morgan PJ, Hubner R, Rolfs A, Frech MJ.
Stem Cells and Development 2013 Sep; 22(18):2477.
Application:WB-Ce, Human, Neural progenitor cells.
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Congenital long QT syndrome.
Crotti L, Celano G, Dagradi F, Schwartz PJ.
Orphanet Journal of Rare Diseases 2008 Jul; 3:18.
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Ca(V)1.2 calcium channel dysfunction causes a multisystem disorder including arrhythmia and autism.
Splawski I, Timothy KW, Sharpe LM, Decher N, Kumar P, Bloise R, Napolitano C, Schwartz PJ, Joseph RM, Condouris K, Tager-Flusberg H, Priori SG, Sanguinetti MC, Keating MT.
Cell 2004 Oct; 119(1):19.
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Spontaneous Calcium Transients in Human Neural Progenitor Cells Mediated by Transient Receptor Potential Channels.
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