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Last updated: 2016/11/27
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KCNJ4 monoclonal antibody, clone S25-35

  • Catalog # : MAB6659
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against partial recombinant KCNJ4.
  • Immunogen:
  • Recombinant fusion protein corresponding to amino acids 390-445 of human KCNJ4.
  • Host:
  • Mouse
  • Reactivity:
  • Human, Mouse, Rat
  • Specificity:
  • Detects ~45KDa. No cross-reactivity against Kir2.1 or Kir2.2.
  • Form:
  • Liquid
  • Isotype:
  • IgG1
  • Recommend Usage:
  • Western Blot (1-10 ug/mL)
    Immunohistochemistry (0.1-1.0 ug/mL)
    Immunocytochemistry (0.1-1.0 ug/mL)
    Immunofluorescence (1.0-10 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.4 (50% glycerol, 0.09% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis of human cell line mixed lysate with Kcnc1 monoclonal antibody, clone S16B-8 (Cat # MAB6659).
  • Immunohistochemistry
  • Immunofluorescence
  • Immunofluorescence
  • Immunofluorescence staining in human hippocampus with KCNJ4 monoclonal antibody, clone S25-35 (Cat # MAB6659).
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Immunohistochemistry
  • Gene Information
  • Entrez GeneID:
  • 3761
  • Gene Name:
  • KCNJ4
  • Gene Alias:
  • HIR,HIRK2,HRK1,IRK3,Kir2.3,MGC142066,MGC142068
  • Gene Description:
  • potassium inwardly-rectifying channel, subfamily J, member 4
  • Gene Summary:
  • Several different potassium channels are known to be involved with electrical signaling in the nervous system. One class is activated by depolarization whereas a second class is not. The latter are referred to as inwardly rectifying K+ channels, and they have a greater tendency to allow potassium to flow into the cell rather than out of it. This asymmetry in potassium ion conductance plays a key role in the excitability of muscle cells and neurons. The protein encoded by this gene is an integral membrane protein and member of the inward rectifier potassium channel family. The encoded protein has a small unitary conductance compared to other members of this protein family. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000028922,hippocampal inward rectifier potassium channel,inward rectifier K+ channel Kir2.3,potassium inwardly-rectifying channel J4
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