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Last updated: 2016/10/16
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KCNQ4 monoclonal antibody, clone S43-6

  • Catalog # : MAB6656
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against partial recombinant KCNQ4.
  • Immunogen:
  • Recombinant fusion protein corresponding to amino acids 2-77 of human KCNQ4.
  • Host:
  • Mouse
  • Reactivity:
  • Human, Mouse, Rat
  • Specificity:
  • Detects ~77KDa.
  • Form:
  • Liquid
  • Isotype:
  • IgG1
  • Recommend Usage:
  • Western Blot (1-10 ug/mL)
    Immunohistochemistry (0.1-1.0 ug/mL)
    Immunocytochemistry (0.1-1.0 ug/mL)
    Immunofluorescence (1.0-10 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.4 (50% glycerol, 0.09% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • Western blot analysis of rat tissue (a blend of rat skeletal muscle, heart, brain, kidney, liver, lung, pancreas, testes, spleen, and thymus) mixed lysate with KCNQ4 monoclonal antibody, clone S43-6 (Cat # MAB6656).
  • Immunocytochemistry
  • Immunofluorescence
  • Immunofluorescence
  • Immunofluorescence staining in human hippocampus with KCNQ4 monoclonal antibody, clone S43-6 (Cat # MAB6656).
  • Immunoprecipitation
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • Immunocytochemistry
  • Immunoprecipitation
  • Gene Information
  • Entrez GeneID:
  • 9132
  • Gene Name:
  • KCNQ4
  • Gene Alias:
  • DFNA2,KV7.4
  • Gene Description:
  • potassium voltage-gated channel, KQT-like subfamily, member 4
  • Gene Summary:
  • The protein encoded by this gene forms a potassium channel that is thought to play a critical role in the regulation of neuronal excitability, particularly in sensory cells of the cochlea. The current generated by this channel is inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. The encoded protein can form a homomultimeric potassium channel or possibly a heteromultimeric channel in association with the protein encoded by the KCNQ3 gene. Defects in this gene are a cause of nonsyndromic sensorineural deafness type 2 (DFNA2), an autosomal dominant form of progressive hearing loss. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000009219,potassium channel KQT-like 4,potassium voltage-gated channel KQT-like protein 4
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